THE DIVERSITY OF SERUM ANTI-DSG3 IGG SUBCLASSES HAS A MAJOR IMPACT ON PEMPHIGUS ACTIVITY AND IS PREDICTIVE OF RELAPSES AFTER TREATMENT WITH RITUXIMAB

The Diversity of Serum Anti-DSG3 IgG Subclasses Has a Major Impact on Pemphigus Activity and Is Predictive of Relapses After Treatment With Rituximab

IntroductionWe studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV).MethodsWe longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment) in sera from PV patients, using an addressable-laser bead immunoassay (ALBIA).The in vitro pathogeni

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Deterioration mechanism of loess from Ili valley region of China under wet and dry cycles: evidences from shear tests

The properties of loess in the Ili region of China are significantly affected by repeated cycles of rainfall and evaporation.It is thus essential to investigate the deterioration mechanism of loess subjected to the wet and dry cycles.This paper employs various methods, including the direct shear and triaxial shear tests, as well as the scanning ele

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